I just set up a site using Django-CMS over at Pomme d'Api Preschool. Overall, I am pretty impressed. I really like the Django admin interface enhancements as well as the site overlay editing feature. One of the best things it he use of django-filer, a file management tool to manage all the uploads to the site. It's awesome and it makes me want to throw out this home page completely and switch over to Django-CMS. Image handling in Drupal has always sucked and still does. The fact that there was no official media/image handling in Drupal 6 sucks, and it's made worse by the fact that there is no real upgrade path to Drupal 7 for media/images, especially if you're like me and you used the "Image" and "image-assist" modules, two of the most popular modules dealing with images.
Django-CMS is pretty powerful and so far it has allowed me to do pretty much anything I have wanted to do.